Shogo Kawaguchi Selected Research

Toll-Like Receptor 3

1/2024	Possible involvement of DExD/H box helicase 60 in synovial inflammation of rheumatoid arthritis: role of toll-like receptor 3 signaling.
12/2023	Expression of interferon-stimulated gene 20 (ISG20), an antiviral effector protein, in glomerular endothelial cells: possible involvement of ISG20 in lupus nephritis.
12/2022	Glomerular endothelial expression of type I IFN-stimulated gene, DExD/H-Box helicase 60 via toll-like receptor 3 signaling: possible involvement in the pathogenesis of lupus nephritis.
9/2021	Expression of IFN-induced transmembrane protein 1 in glomerular endothelial cells.
1/2021	Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes.
11/2020	Endothelial expression of fractalkine (CX3CL1) is induced by Toll-like receptor 3 signaling in cultured human glomerular endothelial cells.
1/2018	Gnetin C suppresses double-stranded RNA-induced C-C motif chemokine ligand 2 (CCL2) and CCL5 production by inhibiting Toll-like receptor 3 signaling pathway.
1/2017	Cylindromatosis (CYLD), a Deubiquitinase, Attenuates Inflammatory Signaling Pathways by Activating Toll-Like Receptor 3 in Human Mesangial Cells.
4/2016	Interferon-stimulated gene (ISG) 60, as well as ISG56 and ISG54, positively regulates TLR3/IFN-β/STAT1 axis in U373MG human astrocytoma cells.
5/2015	Desferrioxamine, an iron chelator, inhibits CXCL10 expression induced by polyinosinic-polycytidylic acid in U373MG human astrocytoma cells.

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Shogo Kawaguchi Research Topics

Disease

12	Inflammation (Inflammations) 01/2024 - 01/2016
8	Melanoma (Melanoma, Malignant) 02/2022 - 10/2015
7	Lupus Nephritis 12/2023 - 10/2015
6	Glomerulonephritis 12/2023 - 10/2015
5	Neuroblastoma 04/2024 - 11/2010
4	Alzheimer Disease (Alzheimer's Disease) 06/2022 - 05/2015
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 12/2022 - 12/2021
3	Neoplasms (Cancer) 12/2022 - 01/2010
3	Virus Diseases (Viral Diseases) 11/2022 - 09/2021
3	Colitis 07/2022 - 09/2009
3	Chronic Renal Insufficiency 09/2021 - 01/2017
3	Astrocytoma (Pilocytic Astrocytoma) 01/2018 - 05/2015
2	Rheumatoid Arthritis 01/2024 - 01/2021
2	Obesity 03/2023 - 01/2022
2	Ulcerative Colitis 07/2022 - 09/2009
2	Non-alcoholic Fatty Liver Disease 01/2022 - 12/2019
1	Central Nervous System Viral Diseases 04/2024
1	Osteoarthritis 01/2024
1	Endotoxemia 03/2023
1	Carcinogenesis 01/2023
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2023
1	Cardiomegaly (Heart Hypertrophy) 12/2022
1	Left Ventricular Dysfunction 12/2022
1	Hypertrophy 12/2022
1	Fibrosis (Cirrhosis) 12/2022
1	Heart Failure 12/2022
1	Myocardial Infarction 12/2022
1	Pulmonary Arterial Hypertension 07/2022
1	Weight Loss (Weight Reduction) 07/2022
1	Nervous System Diseases (Neurological Disorders) 06/2022
1	Disease Progression 02/2022
1	Fatty Liver 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Infections 01/2022
1	Acute Kidney Injury (Acute Renal Failure) 09/2021
1	Carcinoma (Carcinomatosis) 06/2018
1	Adenocarcinoma 06/2018
1	Acute Abdomen 06/2018
1	Polyps 06/2018
1	Nephritis 01/2018
1	Purpura 01/2018
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018
1	IGA Glomerulonephritis (IGA Nephropathy) 10/2015
1	Parkinson Disease (Parkinson's Disease) 05/2015

Drug/Important Bio-Agent (IBA)

10	Toll-Like Receptor 3IBA 01/2024 - 05/2015
7	Proteins (Proteins, Gene)FDA Link 01/2024 - 01/2016
5	ChemokinesIBA 04/2024 - 10/2015
5	InterferonsIBA 12/2023 - 10/2015
5	Tretinoin (Retinoic Acid)FDA LinkGeneric 02/2022 - 10/2015
5	Poly I-CIBA 01/2019 - 05/2015
4	Antiviral Agents (Antivirals)IBA 12/2023 - 12/2019
3	RNA Helicases (RNA Helicase)IBA 01/2024 - 12/2019
3	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2022 - 10/2015
3	Messenger RNA (mRNA)IBA 12/2022 - 01/2022
3	Interferon Type IIBA 12/2022 - 01/2016
3	Dextran SulfateIBA 07/2022 - 09/2009
2	LigandsIBA 04/2024 - 01/2018
2	Indigo Carmine (Indigo Blue)IBA 03/2023 - 07/2022
2	tryptanthrineIBA 10/2022 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 06/2022 - 01/2019
2	Chloroquine (Aralen)FDA LinkGeneric 12/2021 - 11/2017
2	CytokinesIBA 12/2019 - 10/2015
2	ResveratrolIBA 01/2018 - 01/2018
2	Amyloid beta-PeptidesIBA 01/2018 - 05/2015
2	Peptides (Polypeptides)IBA 01/2018 - 05/2015
2	gnetin CIBA 01/2018 - 01/2018
2	Amyloid (Amyloid Fibrils)IBA 01/2018 - 05/2015
1	resiquimodIBA 04/2024
1	NF-kappa B (NF-kB)IBA 04/2024
1	MucinsIBA 03/2023
1	auraptenIBA 12/2022
1	Tacrolimus (Prograf)FDA LinkGeneric 07/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2022
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 07/2022
1	Interleukin-10 (Interleukin 10)IBA 07/2022
1	AntigensIBA 02/2022
1	2-mercaptopurineIBA 01/2022
1	Dietary ProteinsIBA 01/2022
1	SaltsIBA 01/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2022
1	Plasminogen Activator Inhibitor 1IBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	Antimalarials (Antimalarial Agents)IBA 12/2021
1	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 12/2021
1	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 09/2021
1	Chemokine CX3CL1IBA 11/2020
1	ImmunosorbentsIBA 01/2019
1	Viral RNAIBA 01/2019
1	EnzymesIBA 01/2019
1	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2019
1	VimentinIBA 06/2018
1	Keratins (Keratin)IBA 06/2018
1	E-SelectinIBA 01/2018
1	Chemotactic FactorsIBA 01/2018
1	Small Interfering RNA (siRNA)IBA 01/2016
1	IronIBA 05/2015
1	Deferoxamine (Desferal)FDA LinkGeneric 05/2015
1	Chelating AgentsIBA 05/2015

Therapy/Procedure

1	Gastrectomy 06/2018
1	Aftercare (After-Treatment) 01/2018